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How does this medication work? What will it do for me?
Telmisartan belongs to a class of medications known as angiotensin II receptor antagonists. These medications reduce blood pressure by blocking the actions of a chemical (angiotensin II) that causes blood vessels to constrict or tighten. It is used to treat mild-to-moderate high blood pressure.
When blood pressure is allowed to remain high for a long time, the blood vessels of the heart, kidneys, and brain may become damaged. This puts a person at increased risk for heart attack and stroke as well as kidney failure and blindness. Keeping blood pressure in the normal range can reduce the risk for these conditions.
Telmisartan is also used to reduce the risk of death caused by a heart attack or stroke, for people who cannot use another type of medication called angiotensin-converting enzyme inhibitor.
What form(s) does this medication come in?
Each white, oblong, uncoated tablet, engraved with "rph" on one side and "T72" on the other side, contains 40 mg telmisartan. Nonmedicinal ingredients: hydroxypropyl methylcellulose, magnesium stearate, mannitol, meglumine, povidone, sodium hydroxide, and sorbitol.
Each white, oblong, uncoated tablet, engraved with "rph" on one side and "T71" on the other side, contains 80 mg telmisartan. Nonmedicinal ingredients: hydroxypropyl methylcellulose, magnesium stearate, mannitol, meglumine, povidone, sodium hydroxide, and sorbitol.
How should I use this medication?
The recommended adult dose of telmisartan is 80 mg once a day at approximately the same time each day, with or without food. It will take about 2 weeks for reductions in blood pressure to become noticeable and another 2 weeks until the full effects of the medication are realized. People with reduced liver function are usually given 40 mg once daily to start.
It is important to take this medication regularly and to follow your doctor’s instructions regarding blood pressure monitoring to ensure that you are getting the maximum benefit from the medication.
If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
Store telmisartan at normal room temperature in a dry place (not in the bathroom) and keep it out of the reach of children. Do not remove tablets from their blister-pack until you are ready to take them.
Who should NOT take this medication?
Do not take telmisartan if you:
- are allergic to telmisartan or to any of the ingredients of the medication
- have experienced angioedema as a reaction to any angiotensin receptor blocker (ARB)
- are pregnant or plan to become pregnant
- are breast-feeding
- have diabetes or kidney disease and are taking the medication aliskiren
- are allergic to certain sugars (fructose and/or sorbitol intolerant)
What side effects are possible with this medication?
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
- abdominal pain
- back or leg pain
- difficulty sleeping
- dry mouth
- eczema or skin rash
- joint pain
- muscle cramps or spasms
- upper respiratory tract infection (such as colds or sinus infections)
- upset stomach
Although most of these side effects listed below don’t happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
- chest pain
- dizziness, fainting, or lightheadedness
- symptoms of low blood sugar (e.g., cold sweat, cool pale skin, headache, fast heartbeat, weakness)
- shortness of breath
- signs of depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)
- signs of kidney problems (e.g., decreased urination, nausea, vomiting, swelling of the feet and ankles)
- signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
- signs of too much potassium in the body (e.g., irregular heartbeat, muscle weakness, generally feeling unwell)
- swelling of ankles, feet, or hands
- symptoms of a urinary tract infection (e.g., pain when urinating, urinating more often than usual, low back or flank pain)
- unexplained muscle pain, tenderness, or weakness
- vision changes
Stop taking the medication and seek immediate medical attention if any of the following occur:
- signs of a serious blood infection (e.g., chills, confusion, fever or low body temperature, shakiness, irregular heartbeat)
- signs of a serious allergic reaction (e.g., swelling of face, lips, tongue, or throat; hives; difficulty breathing)
Are there any other precautions or warnings for this medication?
Drowsiness/reduced alertness: Telmisartan may cause drowsiness or dizziness, affecting your ability to drive or operate machinery. Avoid these and other hazardous tasks until you have determined how this medication affects you.
Kidney disease: Telmisartan may affect kidney function, especially for people who already have kidney problems. Taking this medication along with the medication aliskiren or an angiotensin-converting enzyme inhibitor (ACEI) further increases the risk of kidney problems. If you have reduced kidney function or kidney disease, renal artery stenosis (narrowing of blood vessels in the kidneys), or congestive heart failure, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
If you experience symptoms of decreased kidney function, such as puffy hands, face or feet, high blood pressure, unusual muscle cramping, or darkened urine, contact your doctor as soon as possible.
Liver disease: Telmisartan is removed from the body by the liver. On rare occasions, it may cause liver problems. If you have liver disease or decreased liver function, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.
Low blood pressure: If you have orthostatic hypotension (a sudden drop in blood pressure caused by standing up, which may lead to fainting), you should be cautious while taking telmisartan, as it can worsen the condition. The first time this medication is taken, it may cause dizziness, lightheadedness, or fainting. This may be reduced by taking the medication in a sitting position and being careful to rise slowly to a standing position. The dizziness usually improves after the first dose, but if the medication is stopped and then started again, it may reappear. Your doctor may also adjust the dose.
Potassium levels: This medication may affect potassium levels in the blood, especially when used for heart failure, or when taken with other medications called ACE inhibitors, aliskiren, or diuretics such as spironolactone. Your doctor will monitor your potassium levels while on this medication. Avoid using salt substitutes that contain potassium while you are taking telmisartan.
Pregnancy: Telmisartan may cause severe harm to an unborn fetus and should not be taken during pregnancy. If you discover you are pregnant while taking this medication, stop taking the medication and tell your doctor at once.
Breast-feeding: It is not known if telmisartan passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children.
What other drugs could interact with this medication?
There may be an interaction between telmisartan and any of the following:
- alpha-blockers (e.g., alfuzosin, doxazosin, silodosin, tamsulosin)
- amphetamines (e.g., dextroamphetamine, lisdexamfetamine)
- angiotensin-converting enzyme inhibitors (ACEIs; captopril, enalapril, ramipril)
- other angiotensin receptor blockers (ARBs; e.g., candesartan, irbesartan, losartan)
- antipsychotics (e.g., clozapine, olanzapine, quetiapine, risperidone)
- barbiturates (e.g., secobarbital, phenobarbital)
- beta-adrenergic blockers (e.g., atenolol, propranolol, sotalol)
- calcium channel blockers (e.g., amlodipine, diltiazem, nifedipine, verapamil)
- diuretics (water pills; e.g., furosemide, hydrochlorothiazide, triamterene)
- isosorbide dinitrate or isosorbide mononitrate
- low molecular weight heparins (e.g., dalteparin, enoxaparin, tinzaparin)
- monoamine oxidase inhibitors (MAOIs; e.g., moclobemide, phenelzine, rasagiline, selegiline, tranylcypromine)
- nonsteroidal anti-inflammatory drugs (NSAIDs; e.g., naproxen, ibuprofen)
- phosphodiesterase 5 inhibitors (e.g., sildenafil, tadalafil, vardenafil)
- potassium supplements or medications that increase potassium in the blood
- selective serotonin reuptake inhibitors (SSRIs; e.g., citalopram, fluoxetine, paroxetine, sertraline)
- sodium phosphates
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
All material copyright MediResource Inc. 1996 – 2022. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Teva-Telmisartan