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Terazosin by Pro Doc
How does this medication work? What will it do for me?
Terazosin belongs to the family of medications called antihypertensives, specifically the group known as alpha 1-blockers. Terazosin is used to treat mild-to-moderate high blood pressure. It relaxes blood vessels, allowing blood to flow through them more easily.
Terazosin is also used to treat enlarged prostate (benign prostatic hyperplasia or BPH). For BPH, terazosin helps to relax the muscles in the prostate and bladder. This helps to improve urine flow and decrease symptoms of BPH. Terazosin does not slow or stop the progression of enlarged prostate.
What form(s) does this medication come in?
This medication is available as 1 mg, 2 mg, 5 mg, and 10 mg tablets.
How should I use this medication?
The recommended adult dose of terazosin for high blood pressure starts at 1 mg at bedtime and is slowly increased until the desired blood pressure response is achieved. The usual dose ranges from 1 mg to 5 mg daily. The dose for high blood pressure is usually taken once or twice a day.
The recommended adult dose of terazosin to treat an enlarged prostate starts at 1 mg at bedtime, with increases at weekly intervals to 2 mg, 5 mg, or 10 mg once daily to achieve the desired improvement of symptoms. It may take 2 to 4 weeks of treatment before you see an improvement of your symptoms.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If it has been more than a few days since your last dose, talk to your doctor; you may need to restart at the 1 mg dose. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Who should NOT take this medication?
Who should not take this medication?
Do not take this medication if you:
- are allergic to terazosin or any ingredients of this medication
- are allergic to quinazoline-type medications
What side effects are possible with this medication?
- abdominal pain or discomfort
- back or joint pain
- blurred vision
- decreased interest in sexual activity
- decreased sexual ability
- difficulty sleeping
- dizziness or lightheadedness, especially when getting up from a lying or sitting position
- dry mouth
- increased need to urinate or urinating more often than usual
- stuffy nose
- unusual tiredness or weakness
Check with your doctor as soon as possible if any of the following side effects occur:
- blood pressure changes
- blurred vision
- chest pain
- fainting (sudden)
- fast or irregular heartbeat
- pounding heartbeat
- shortness of breath
- signs of depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)
- skin rash
- swelling of feet or lower legs
- symptoms of a urinary tract infection (e.g., pain when urinating, urinating more often than usual, low back or flank pain, strong odour)
- weight gain
Stop taking the medication and seek immediate medical attention if any of the following occur:
- painful, prolonged erection (lasting longer than 4 hours)
- signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)
- trouble breathing
Are there any other precautions or warnings for this medication?
Blood pressure: The first few doses of terazosin can cause extreme lowering of blood pressure, especially when moving from a lying or sitting position to a standing position. Sometimes even loss of consciousness can occur. A similar effect may occur if the medication is taken again after stopping it for more than a few doses, if the dose is rapidly increased, or if another blood-pressure-lowering medication is added.
The likelihood of this effect can be minimized by starting the dose of terazosin at 1 mg at bedtime, by increasing the dosage slowly, and by starting any additional blood-pressure-lowering medications with caution. If you are also taking phosphodiesterase 5 inhibitors (e.g., sildenafil, tadalafil, vardenafil) discuss with your doctor whether any special monitoring is needed.
While temporary loss of consciousness is the most severe blood-pressure-lowering effect of terazosin, other symptoms of lowered blood pressure, such as dizziness, lightheadedness, and palpitations are more common. If these symptoms occur, lie down and wait for a few minutes before standing to prevent their recurrence, then get up very gradually.
Disease progression: Terazosin does not slow or stop the progression of enlarged prostate.
Drowsiness/reduced alertness: Because of the risk of extreme lowering of blood pressure, avoid driving or hazardous tasks for 12 hours after the initial dose of terazosin, after the dose is increased, and after interruption of therapy when treatment is resumed.
Avoid situations where dizziness, lightheadedness, or temporary loss of consciousness could result in injury.
Fainting: Terazosin can cause extreme lowering of blood pressure and possibly fainting. If you have a history of micturition syncope (a condition where fainting occurs during or after urination), you should not take terazosin. Talk to your doctor if you have any concerns.
Kidney, bladder, and urinary problems: If you have reduced kidney function, bladder problems, or urinary problems, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Prostate cancer: Prostate cancer and enlarged prostate (BPH) have many of the same symptoms and it is possible for men to have both diseases at the same time. Terazosin is not used to treat prostate cancer. Your doctor may perform tests to rule out prostate cancer before starting you on terazosin treatment.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: It is not known if terazosin passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children.
Seniors: People over 65 years of age may be at an increased risk of blood pressure decreases, especially when moving from a lying or sitting position to a standing position.
What other drugs could interact with this medication?
There may be an interaction between terazosin and any of the following:
- other alpha 1 blockers (e.g., doxazosin, prazosin, tamsulosin)
- other medications that lower blood pressure (antihypertensives), such as beta-blockers (e.g., metoprolol, propranolol)
- alpha agonists (e.g., clonidine, methyldopa)
- amphetamines (e.g., dextroamphetamine, lisdexamphetamine)
- angiotensin converting enzyme inhibitors (ACEIs; captopril, enalapril, ramipril)
- angiotensin receptor blockers (ARBs; e.g., candasartan, irbesartan, losartan)
- barbiturates (e.g., butalbital, pentobarbital phenobarbital)
- beta-adrenergic blockers (e.g., atenolol, propranolol, sotalol)
- calcium channel blockers (e.g., amlodipine, diltiazem, nifedipine, verapamil)
- diuretics (water pills; e.g., furosemide, hydrochlorothiazide, triamterene)
- monoamine oxidase inhibitors (MAOIs; e.g., moclobemide, phenelzine, rasagiline, selegiline, tranylcypromine)
- nitrates (e.g., nitroglycerin, isosorbide dinitrate, isosorbide mononitrate)
- phosphodiesterase 5 inhibitors (e.g., sildenafil, tadalafil, vardenafil)
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
All material copyright MediResource Inc. 1996 – 2022. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Terazosin-by-Pro-Doc