Medication Search: ratio-Fenofibrate MC
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How does this medication work? What will it do for me?
Fenofibrate belongs to the class of medications known as fibrates. It is used in addition to diet and exercise to treat people with abnormal cholesterol levels.
Fenofibrate (micronized) reduces bad cholesterol (low density lipoproteins [LDL] and very low density lipoproteins [VLDL]) and triglycerides in your blood. It also increases good cholesterol (high density lipoprotein [HDL]) levels. Bringing cholesterol levels in the blood into the desired range has been shown to reduce the risks associated with heart disease, such as heart attack.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
What form(s) does this medication come in?
Each hard gelatin capsule, with an orange opaque body imprinted "rph 183" and orange opaque cap imprinted with "200" contains 200 mg of fenofibrate. Nonmedicinal ingredients: hydroxypropyl cellulose, lauroyl macrogolglyceride, and polyethylene glycol; capsule shell: FD&C Red No. 3, gelatin, titanium dioxide, and yellow iron oxide.
How should I use this medication?
The usual daily adult dose of micronized fenofibrate is 200 mg. This may be taken as a single 200 mg capsule once daily with or after the main meal. Alternatively, three 67 mg capsules can be taken daily in 2 or 3 divided doses with or after meals. The maximum recommended total daily dose is 200 mg.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Who should NOT take this medication?
Do not take micronized fenofibrate if you:
- are allergic to fenofibrate or to any of the ingredients of the medication
- are allergic to other medications of the fibrate class (e.g., gemfibrozil, bezafibrate, clofibrate)
- are allergic to peanuts, arachis oil, or soya lecithin
- are pregnant or breast-feeding
- are taking a "statin" cholesterol-lowering medication (e.g., atorvastatin, lovastatin) and have or are at risk of developing muscle problems
- has a disorder known as type 1 hyperlipoproteinemia
- have had a severe skin reaction to other fibrates or ketoprofen
- have liver disease, kidney disease, or gallbladder disease
- have acute or chronic pancreatitis
- are less than 18 years of age
What side effects are possible with this medication?
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
- red, itchy skin
- runny nose
- stomach pain
Although most of these side effects listed below don’t happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
- severe stomach pain, nausea, or vomiting
- signs of liver problems (e.g., dark urine, general feeling of being unwell, loss of appetite, nausea, vomiting, or yellowing of the eyes or skin)
- unexplained muscle pain, tenderness, weakness, chills, or fever
Stop taking the medication and seek immediate medical attention if any of the following occur:
- signs of a serious allergic reaction (e.g., hives, swelling of the face or throat, difficulty breathing)
- signs of a blood clot (e.g., breathlessness, coughing up blood; pains in chest, groin, or leg – especially in calf of leg)
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Are there any other precautions or warnings for this medication?
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Blood components: Small, temporary decreases in red and white blood cell counts have been observed in people using this medication. Your doctor will check for this with blood tests during the first year of treatment.
Combination therapy: The use of fenofibrate and "statin" medications (e.g., atorvastatin, lovastatin, simvastatin) at the same time may increase the risk of muscle-related side effects. Talk to your doctor about the risks and benefits of taking the two types of medications together.
Gallbladder disease: For some people, fenofibrate may cause the formation of gallstones. If you experience abdominal or stomach pain, gas, nausea, or bloating (especially after eating high-fat foods), contact your doctor.
Kidney function: If you have reduced kidney function, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Liver function: If you have reduced liver function or liver disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Skeletal muscle: Treatment with this type of medication has been associated on rare occasions with muscle pain, usually in people with reduced kidney function. Contact your doctor as soon as possible if you notice unexplained muscle pain, tenderness, or weakness, particularly if you also have malaise (a general feeling of illness) or fever.
Pregnancy: The safety of this medication has not been established for pregnant women. This medication should not be used by pregnant women.
Breast-feeding: It is not known if fenofibrate passes into breast milk. If you are a breast-feeding mother and are taking fenofibrate, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of the medication have not been established for use by children under the age of 18.
Seniors: Seniors are more likely to have reduced kidney function and may need lower doses of this medication.
What other drugs could interact with this medication?
There may be an interaction between fenofibrate (micronized) and any of the following:
- cholestyramine resin
- "statin" medications (e.g., atorvastatin, lovastatin, simvastatin)
- sulfonylureas (e.g. glyburide, chlorpropamide)
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
All material copyright MediResource Inc. 1996 – 2023. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/ratio-Fenofibrate-MC