All material © 1996-2015 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.
triamterene – hydrochlorothiazide
This combination product contains 2 medications: triamterene and hydrochlorothiazide. Both these medications belong to the class of medications called diuretics (“water pills”). They are used in combination to treat edema (fluid retention) that occurs with congestive heart failure and disorders of the liver and kidney. It is also used to treat mild to moderate high blood pressure.
This medication works by making the body
lose excess water and salt. Triamterene, called a potassium-sparing diuretic,
helps the body to retain potassium, while hydrochlorothiazide causes potassium
to be lost from the body. Therefore, potassium supplements are usually not required
with this medication.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure
why you are taking this medication, speak to your doctor. Do not stop taking
this medication without consulting your doctor.
Do not give this
medication to anyone else, even if they have the same symptoms as you do.
It can be harmful for people to take this medication if their doctor has not prescribed
Nu-Triazide is no longer being manufactured for sale in Canada. For brands that may still be available, search under triamterene – hydrochlorothiazide. This article is being kept available for reference purposes only. If you are using this medication, speak with your doctor or pharmacist for information about your treatment options.
Each triamterene – hydrochlorothiazide
tablet contains triamterene 50 mg and hydrochlorothiazide 25 mg. The usual
starting dose to treat edema (fluid retention) or high blood pressure
is 1 tablet twice daily after meals. The maximum daily dose is 4 tablets divided into 2 doses.
Your doctor will increase, decrease,
or leave the dose the same depending on your response to the medication. If more
than 1 tablet per day is needed, it should be taken in 2 divided doses. If only
one dose is needed, it should be taken in the morning after breakfast.
things can affect the dose of medication that a person needs, such as body weight,
other medical conditions, and other medications. If your doctor has recommended
a dose different from the ones listed here, do not change the way that you
are taking the medication without consulting your doctor.
It is important
to take this medication exactly as prescribed by your doctor. If you miss a dose,
take it as soon as possible and continue with your regular schedule. If it is
almost time for your next dose, skip the missed dose and continue with your regular
dosing schedule. Do not take a double dose to make up for a missed one.
If you are not sure what to do after missing a dose, contact your doctor or pharmacist
Store this medication at room temperature, out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Do not take this medication if you:
medications can cause side effects. A side effect is an unwanted response
to a medication when it is taken in normal doses. Side effects can be mild or
severe, temporary or permanent.
The side effects listed below are not experienced
by everyone who takes this medication. If you are concerned about side effects,
discuss the risks and benefits of this medication with your doctor.
following side effects have been reported by at least 1% of people taking this
medication. Many of these side effects can be managed, and some may go away on
their own over time.
Contact your doctor if you experience these side
effects and they are severe or bothersome. Your pharmacist may be able to advise
you on managing side effects.
Although most of these
side effects listed below don’t happen very often, they could lead to serious
problems if you do not seek medical attention.
with your doctor as soon as possible if any of the following side effects occur:
Signs of changes in potassium
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience
side effects other than those listed. Check with your doctor if you notice
any symptom that worries you while you are taking this medication.
begin using a medication, be sure to inform your doctor of any medical conditions
or allergies you may have, any medications you are taking, whether you are pregnant
or breast-feeding, and any other significant facts about your health. These factors
may affect how you should use this medication.
Allergy: Some people who are allergic to sulfonamide antibiotics also experience allergic reactions to triamterene – hydrochlorothiazide because of the hydrochlorothiazide component. Before you take this medication, inform your doctor about any previous adverse reactions you have had to medications, especially sulfonamide (sulfa) antibiotics.
Contact your doctor at once if you experience signs of an allergic reaction such as skin rash, itching, difficulty breathing, or swelling of the face and throat.
Diabetes: People with diabetes may find that their blood sugar level is less controlled when taking triamterene – hydrochlorothiazide. If you have diabetes, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Gout: This medication may cause a flare-up of gout symptoms. If you have gout or a history of gouty arthritis, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Kidney stones: Triamterene has been found in kidney stones. If you have kidney stones or a history of kidney stones, discuss with your doctor
how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Potassium levels: Increased blood levels of potassium, though uncommon, are potentially the most severe side effect with this medication. This is more likely to occur if you are 60 years and older.
Warning signs or symptoms of high potassium include numbness, muscular weakness, fatigue, paralysis of the extremities, and slow heart rate. If this condition occurs, stop taking the medication.
Potassium supplements: Potassium supplementation, either in the form of medication or as a potassium-rich diet, should not be used at the same time as triamterene – hydrochlorothiazide. Triamterene helps recycle potassium from the urine, back into the body. When it is combined with potassium supplements, high levels of potassium in the blood may result.
Low levels of potassium may also occur for some of the people taking this medication because of the potassium-lowering effect of hydrochlorothiazide.
Pregnancy: Hydrochlorothiazide crosses the placenta and may affect an unborn baby. Triamterene – hydrochlorothiazide should
not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: Hydrochlorothiazide passes into breast milk, and triamterene may pass into breast milk. If you are a breast-feeding mother and are taking triamterene – hydrochlorothiazide, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children.
There may be an interaction between triamterene
– hydrochlorothiazide and any of the following:
you are taking any of these medications, speak with your doctor or pharmacist.
Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications
does not always mean that you must stop taking one of them. Speak to your
doctor about how any drug interactions are being managed or should be managed.
other than those listed above may interact with this medication. Tell your
doctor or prescriber about all prescription, over-the-counter (non-prescription),
and herbal medications you are taking. Also tell them about any supplements you
take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can
affect the action of many medications, you should let your prescriber know if
you use them.
All material copyright MediResource Inc. 1996 – 2019. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Nu-Triazide
All material © 1996-2018 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.