Learn about many of the available medications in our database.
diphtheria - haemophilus b - pertussis - polio - tetanus vaccine
How does this medication work? What will it do for me?
It works by increasing a child’s defenses against the bacteria and viruses that cause these infections, by stimulating the production of the child’s own antibodies. These antibodies remain in the body until needed to fight off the viruses and bacteria causing these infections if the child is exposed to them.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why your child is being given this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
What form(s) does this medication come in?
Each 0.5 mL dose of sterile suspension for injection contains not less than 25 limit of flocculation (Lf) [30 International Units (IU)] of diphtheria toxoid; 10 Lf (40 IU) of tetanus toxoid; 25 μg of pertussis toxoid; 25 μg of filamentous haemagglutinin; 8 μg of pertactin; 40 D-antigen units (DU) of type 1 poliovirus; 8 DU type 2 poliovirus; 32 DU type 3 poliovirus; 10 μg of purified polyribosyl-ribitol-phosphate capsular polysaccharide of Haemophilus Influenzae type B covalently bound to 30 μg of tetanus toxoid. Nonmedicinal ingredients: lactose, sodium chloride, aluminum adjuvant (as aluminum salts), Medium 199 (as stabilizer including amino acids, mineral salts and vitamins) and water for injection, residual formaldehyde, polysorbate 80, potassium chloride, disodium phosphate, monopotassium phosphate, glycine and trace amounts of neomycin sulphate, and polymyxin B sulphate.
How should I use this medication?
This medication should be kept in the fridge, not frozen and protected from light.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Who should NOT take this medication?
Your child should not receive this medication if they:
- are allergic to diphtheria, tetanus, pertussis, hepatitis B, poliovirus, or Haemophilus influenzae type b vaccines, or any ingredients of this medication
- are allergic to neomycin, or polymyxin
- have previously had encephalopathy (abnormal brain function) within 7 days of receiving a pertussis-containing vaccine
- are currently experiencing a fever or severe, acute illness
Do not give this medication to children 5 years of age and older.
What side effects are possible with this medication?
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if your child experiences these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
- fever (usually lasts less than 48 hours)
- loss of appetite
- pain, soreness, redness, swelling, or a lump at the place of injection
- unusual crying
Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
- bleeding or bruising more easily
- slowed breathing
- swollen glands
- symptoms of a cold, sinus, or ear infection
- temporary breathing interruptions (more likely to occur with children born at 28 weeks of pregnancy or less)
Stop your child from receiving the medication and seek immediate medical attention if any of the following occur:
- periods of unconsciousness or lack of awareness
- signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)
Be sure to mention any side effect to your doctor, as it may mean that your child is allergic to the vaccine. If so, it would not be safe for them to have more doses of the same type of vaccine.
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while your child is taking this medication.
Are there any other precautions or warnings for this medication?
Before your child receives this medication, be sure to inform your child’s doctor of any medical conditions or allergies they may have, any medications your child is taking, and any other significant facts about your child’s health. These factors may affect how your child should receive this medication.
Allergic reactions: In rare cases, this vaccine may cause severe allergic reactions. For this reason, doctors often ask people to stay in the office for about 30 minutes after having the vaccine so they can receive medical care if an allergic reaction occurs. If you notice signs of a severe allergic reaction in your child (hives; trouble breathing or swallowing; or swelling of the lips, face, throat, or tongue), get medical attention immediately.
Bleeding disorders: If you or your child have a bleeding disorder or are taking medications that make you more likely to bleed (i.e., warfarin, acetylsalicylic acid [ASA]) tell the person giving the injection. There is a risk of excessive bleeding where the injection is given if it is not done carefully.
Immune system: As with any vaccine, this vaccine may not be as effective for people with a weakened immune system (such as those on chemotherapy, people who have had an organ transplant, or people who have HIV).
If your child has a weakened immune system, for any reason, discuss with your doctor how this medication may affect your child’s medical condition, how your child’s medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Infection or fever: This vaccine should not be given to anyone who has an active infection or an illness associated with fever, unless the doctor decides that the benefits outweigh the risks.
Seizures: People who have a history of seizures or seizure disorders may be at an increased risk of experiencing seizures with this vaccine. Your child’s doctor may suggest that you give your child a dose of medication to prevent fever. If your child has a history of seizures, discuss with their doctor whether any special precautions are needed.
Vaccine protection: As with any vaccine, this vaccine may not protect all people who receive it and may not prevent infection in those people already infected with the bacteria or virus.
Pregnancy and breast-feeding: Studies have not been conducted with this vaccine during pregnancy or breast-feeding. This vaccine is not recommended for anyone 5 years of age or older.
Children: Very premature children are at an increased risk of breathing problems as a result of receiving this vaccine. However, the benefit of receiving the vaccination is greater than the risk of side effects, and the vaccine should be given as scheduled, based on the baby’s age. If you have concerns, speak with your child’s doctor.
This vaccine should not be administered to infants younger than 2 months or children 5 years of age or older.
What other drugs could interact with this medication?
There may be an interaction between this vaccine and any of the following:
- immunosuppressants (medications used to treat cancer or autoimmune disease, or prevent organ rejection)
- corticosteroids (e.g., budesonide, dexamethasone, hydrocortisone, fluticasone, prednisone)
- medications to treat cancer (e.g., carboplatin, cyclophosphamide, doxorubicin, ifosfamide, vincristine)
- meningococcal polysaccharide (Groups A/C/Y and W-135) tetanus toxoid conjugate vaccine
If your child is taking any of these medications, speak with your doctor or pharmacist. Depending on the specific circumstances, your doctor may want your child to:
- stop taking one of the medications,
- change one of the medications to another,
- change how they are taking one or both of the medications, or
- leave everything as is.
An interaction between two medications does not always mean that your child must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications your child is taking. Also tell them about any supplements your child takes. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if your child uses them.
All material copyright MediResource Inc. 1996 – 2022. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Infanrix-IPVHib