All material © 1996-2015 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.
Nadroparin belongs to the class of medications known as anticoagulants or antithrombotic agents. These medications reduce the clotting ability of the blood and can reduce the risk of harmful blood clots forming in blood vessels.
Nadroparin is used to prevent and treat deep vein thrombosis (DVT). This condition leads to the formation of blood clots in the blood vessels in the leg. These blood clots can sometimes travel to the lungs and block blood vessels there, resulting in a serious condition known as pulmonary embolism.
Nadroparin is used to prevent DVT and pulmonary embolism in people who are undergoing general surgery or orthopaedic surgery (e.g., hip or knee replacement). Nadroparin may be used to prevent DVT and pulmonary embolism in people who are bedridden or hospitalised due to serious illness (heart failure, severe chest infections, or respiratory failure). It is also used to prevent clotting in people undergoing hemodialysis. Nadroparin is also used to treat unstable angina and heart attack survivors.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.
Fraxiparine® Prefilled Syringes
Each mL of aqueous solution contains 9,500 anti-Xa IU of nadroparin calcium. Single-dose, disposable prefilled glass syringes of 0.2 mL (ungraduated yellow syringes), 1,900 anti-Xa IU; 0.3 mL (ungraduated green syringes), 2,850 anti-Xa IU; 0.4 mL (ungraduated orange syringes), 3,800 anti-Xa IU; 0.6 mL (graduated brown syringes), 5,700 anti-Xa IU; and 1 mL (graduated violet syringes), 9,500 anti-Xa IU. The needle shield of the prefilled syringe may contain latex.
Fraxiparine Forte® Prefilled Syringes
Each mL of aqueous solution contains 19,000 anti-Xa IU of nadroparin calcium. Single-dose, disposable prefilled glass syringes of 0.6 mL (graduated process blue syringes), 11,400 anti-Xa IU; 0.8 mL (graduated magenta syringes), 15,200 anti-Xa IU; and 1 mL (graduated reflex blue syringes), 19,000 anti-Xa IU. The needle shield of the prefilled syringe may contain latex.
The recommended dose depends on the individual and the condition being treated. Nadroparin is injected under the skin (subcutaneously). Your doctor will recommend the dose that is most likely to prevent blood clots but that will not cause you to bleed easily. Your doctor or health care professional will show you how to inject the medication yourself. If you have any questions about how to use the medication, contact your doctor.
To use the medication:
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
It is important to use this medication exactly as prescribed by your doctor. If you miss a dose, contact your doctor or pharmacist. Do not inject a double dose to make up for a missed one.
Store this medication at room temperature and keep it out of the reach of children. Do not refrigerate or freeze the medication.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Do not use this medication if you:
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Bleeding: The most serious risk associated with nadroparin is bleeding in any tissue or organ. It is extremely important to have regular blood tests (as prescribed by your doctor) to ensure that the correct level of blood thinning is occurring. If you have an increased risk of bleeding (for example, if you are over 65, have liver failure, reduced kidney function, high blood pressure, or a history of ulcers), your doctor should closely monitor your condition while you are taking this medication.
Body weight: The safety and efficacy of nadroparin for very heavy people (e.g., over 120 kg) and very light people (e.g., under 45 kg) have not been fully established. If your weight is very high or low, your doctor will monitor you closely while you are taking this medication.
Cardiovascular problems: If you have coronary artery disease or high blood pressure, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Kidney function: Kidney disease or reduced kidney function may cause this medication to build up in the body, causing side effects, including bleeding. If you have reduced kidney function or kidney disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Platelets: While you are using nadroparin, your doctor will also be monitoring your platelet count. If your platelet level drops very suddenly, you may have to stop this medication and switch to another type of medication. Make sure to tell doctors involved in your care if you have had any problems with low platelets or platelet defects in the past.
Potassium levels: Nadroparin may increase blood potassium levels, especially in people who are at risk for high potassium levels (e.g., people with diabetes or who take certain medications). Your doctor will monitor your potassium levels while you are using this medication. If you experience symptoms of high levels of potassium in the blood, such as muscle fatigue, weakness, difficulty moving, abnormal heart rhythms, or nausea, contact your doctor.
Prosthetic heart valves: There have been reports of people with prosthetic heart valves who developed clots in their valves when treated with low-molecular-weight heparin medications such as nadroparin. Your doctor will need to monitor you closely while you are taking nadroparin.
Stomach ulcers: If you have a history of stomach ulcers or bleeding in the digestive system, this medication may cause the condition to reoccur. If you have any symptoms of bleeding in the digestive system, such as bloody, black, or tarry stools, spitting up of blood, vomiting blood or material that looks like coffee grounds, seek medical help immediately.
Pregnancy: The medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: It is not known if nadroparin passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children.
Seniors: People over the age of 65 years are more at risk of bleeding from this medication.
There may be an interaction between nadroparin and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
All material copyright MediResource Inc. 1996 – 2019. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Fraxiparine
All material © 1996-2018 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.