Learn about many of the available medications in our database.
How does this medication work? What will it do for me?
Nateglinide belongs to the group of medications known as oral hypoglycemics or oral antidiabetic agents. Nateglinide is used to control blood glucose for people with type 2 diabetes.
In combination with exercise and a healthy diet, nateglinide works to control blood glucose by increasing the amount of insulin released from the pancreas. It is used when diet, exercise, and weight reduction have not been found to control blood glucose well enough on their own. Nateglinide can be used on its own or in combination with another antidiabetic medication, metformin.
Your doctor may have suggested this medication for conditions other than the ones listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
What form(s) does this medication come in?
July 13, 2015
nateglinide is no longer being manufactured for sale in Canada. This article is being kept available for reference purposes only. If you are using this medication, speak with your doctor or pharmacist for information about your treatment options.
How should I use this medication?
The usual dose of nateglinide is 120 mg, taken before meals. It is usually taken immediately before each meal, but may be taken up to 30 minutes before each meal. The dosage may be adjusted depending on your response to the medication and whether you reach your target blood sugar levels.
If a meal is skipped, the dose usually taken with that meal should not be taken.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
It is important to use this medication exactly as prescribed by the doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Who should NOT take this medication?
Do not take this mediction if you:
- are allergic to nateglinide or to any of the ingredients of the medication
- are pregnant
- have diabetic ketoacidosis
- have type 1 diabetes
What side effects are possible with this medication?
- abdominal or stomach pain
- back pain
- pain in the joints or muscles
- runny or stuffy nose
- sore throat
- swelling in the joints
Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
- symptoms of low blood glucose, including:
- anxious feelings
- behaviour changes similar to being drunk
- blurred vision
- cold sweats
- cool, pale skin
- difficulty thinking
- excessive hunger
- fast heartbeat
- restless sleep
- slurred speech
- unusual tiredness or weakness
Stop taking the medication and seek immediate medical attention if any of the following occur:
- convulsions (seizures)
- signs of a severe allergic reaction (e.g., difficulty breathing, hives, swelling of the face or throat)
Are there any other precautions or warnings for this medication?
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Liver disease: If you have moderate-to-severe liver disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Low blood glucose: This medication may cause low blood glucose (hypoglycemia). Certain people are more sensitive to this effect, including seniors, people who are undernourished, and people who have exercised more strenuously than usual. If you are taking other diabetes medications, have consumed alcohol, or have other medical conditions that cause low blood glucose (e.g., an underactive pituitary or adrenal gland, or kidney problems), you may need to check your blood glucose levels more frequently. Consult your doctor for advice about whether any special monitoring is necessary.
Pregnancy: This medication should not be used during pregnancy. If you think you may be pregnant or if you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: It is not known if nateglinide passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children.
What other drugs could interact with this medication?
There may be an interaction between nateglinide and any of the following:
- beta-adrenergic blockers (e.g., nadolol, propranolol, timolol)
- corticosteroids (e.g., prednisone)
- monoamine oxidase (MAO) inhibitors (e.g., tranylcypromine, phenelzine)
- nonsteroidal anti-inflammatories (NSAIDS; e.g., naproxen, ibuprofen)
- other diabetes medications (e.g., glyburide, metformin)
- salicylates (e.g., ASA)
- sympathomimetics (e.g., epinephrine, pseudoephedrine)
- thiazide diuretics (e.g., hydrochlorothiazide)
- thyroid medications (e.g., levothyroxine)
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
All material copyright MediResource Inc. 1996 – 2022. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Starlix